| Protein Name | vascular endothelial growth factor B |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 7423 |
| Gene Symbol | VEGFB |
| UniProt | P49765 (VEGFB_HUMAN), Q7LAP4 (Q7LAP4_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
67
Total Number of Articles : 62 |
Description |
vascular endothelial growth factor B |
| Gene Summary |
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011] |
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