Protein Name nicotinamide phosphoribosyltransferase
Organism Mus musculus
Gene ID 59027
Gene Symbol

Nampt

UniProt Q99KQ4 (NAMPT_MOUSE)
Relationships Total Number of functionally related compound(s) : 156
Total Number of Articles : 220
Description

nicotinamide phosphoribosyltransferase

Gene Summary

Enables identical protein binding activity and nicotinamide phosphoribosyltransferase activity. Involved in circadian regulation of gene expression; nicotinamide metabolic process; and nicotinamide nucleotide biosynthetic process. Acts upstream of or within NAD biosynthetic process. Located in cytoplasm. Is active in cytosol and mitochondrial matrix. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • nicotinamide phosphoribosyltransferase
  • pre-B-cell colony-enhancing factor 1 homolog
  • 1110035O14Rik
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Properties