| Protein Name | occludin |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 83497 |
| Gene Symbol | Ocln |
| UniProt | Q6P6T5 (OCLN_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
274
Total Number of Articles : 300 |
Description |
occludin |
| Gene Summary |
Predicted to enable protein domain specific binding activity. Involved in several processes, including cellular response to tumor necrosis factor; response to Gram-positive bacterium; and response to interleukin-18. Located in apical plasma membrane and lateral plasma membrane. Biomarker of diabetic retinopathy; metabolic dysfunction and alcohol associated liver disease; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Crohn's disease and pseudo-TORCH syndrome 1. Orthologous to human OCLN (occludin). [provided by Alliance of Genome Resources, May 2025] |
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