| Protein Name | caspase 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 835 |
| Gene Symbol | CASP2 |
| UniProt | P42575 (CASP2_HUMAN), A0A087WYM1 (A0A087WYM1_HUMAN), D3DXD9 (D3DXD9_HUMAN), A0A0S2Z3H1 (A0A0S2Z3H1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
320
Total Number of Articles : 322 |
Description |
caspase 2 |
| Gene Summary |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
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