Protein Name arachidonate 15-lipoxygenase
Organism Mus musculus
Gene ID 11687
Gene Symbol

Alox15

UniProt P39654 (LOX15_MOUSE), A2CF88 (A2CF88_MOUSE)
Relationships Total Number of functionally related compound(s) : 179
Total Number of Articles : 156
Description

arachidonate 15-lipoxygenase

Gene Summary

Enables arachidonate 12(S)-lipoxygenase activity and arachidonate 15-lipoxygenase activity. Involved in several processes, including fatty acid metabolic process; phosphatidylethanolamine biosynthetic process; and positive regulation of actin filament polymerization. Acts upstream of or within bone mineralization. Located in cytosol and plasma membrane. Is expressed in several structures, including alimentary system; liver; nose; peritoneal fluid; and respiratory system. Orthologous to human ALOX15 (arachidonate 15-lipoxygenase). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • polyunsaturated fatty acid lipoxygenase ALOX15
  • 12-LOX
  • 12/15-lipoxygenase
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Properties