Protein Name retinoid X receptor alpha
Organism Homo sapiens
Gene ID 6256
Gene Symbol

RXRA

UniProt P19793 (RXRA_HUMAN), F1D8Q5 (F1D8Q5_HUMAN), Q6P3U7 (Q6P3U7_HUMAN), A0A5F9ZHH6 (A0A5F9ZHH6_HUMAN)
Relationships Total Number of functionally related compound(s) : 659
Total Number of Articles : 1517
Description

retinoid X receptor alpha

Gene Summary

Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]

synonyms
  • retinoic acid receptor RXR-alpha
  • nuclear receptor subfamily 2 group B member 1
  • retinoid X nuclear receptor alpha
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Properties