Protein Name polypeptide N-acetylgalactosaminyltransferase 2
Organism Homo sapiens
Gene ID 2590
Gene Symbol

GALNT2

UniProt Q10471 (GALT2_HUMAN), G3V1S6 (G3V1S6_HUMAN), A0A1L7NY50 (A0A1L7NY50_HUMAN), B7Z6K2 (B7Z6K2_HUMAN)
Relationships Total Number of functionally related compound(s) : 40
Total Number of Articles : 46
Description

polypeptide N-acetylgalactosaminyltransferase 2

Gene Summary

This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

synonyms
  • polypeptide N-acetylgalactosaminyltransferase 2
  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
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Properties