Protein Name myristoylated alanine rich protein kinase C substrate
Organism Rattus norvegicus
Gene ID 25603
Gene Symbol

Marcks

UniProt F1LMW7 (F1LMW7_RAT)
Relationships Total Number of functionally related compound(s) : 91
Total Number of Articles : 77
Description

myristoylated alanine rich protein kinase C substrate

Gene Summary

Enables phosphatidylserine binding activity. Involved in several processes, including activation of phospholipase D activity; positive regulation of protein kinase C activity; and regulation of synapse organization. Located in several cellular components, including dendrite; distal axon; and polymeric cytoskeletal fiber. Is active in several cellular components, including postsynaptic cytoskeleton; presynaptic cytosol; and synaptic membrane. Human ortholog(s) of this gene implicated in Lynch syndrome. Orthologous to human MARCKS (myristoylated alanine rich protein kinase C substrate). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • myristoylated alanine-rich C-kinase substrate
  • Myristoylated alanine-rich protein kinase C substrate
  • protein kinase C substrate 80 kDa protein
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Properties