Protein Name T cell leukemia homeobox 2
Organism Homo sapiens
Gene ID 3196
Gene Symbol

TLX2

UniProt O43763 (TLX2_HUMAN)
Relationships Total Number of functionally related compound(s) : 221
Total Number of Articles : 195
Description

T cell leukemia homeobox 2

Gene Summary

This gene is a member of an orphan homeobox-containing transcription factor family. Studies of the mouse ortholog have shown that the encoded protein is crucial for the development of the enteric nervous system; in humans, loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors. [provided by RefSeq, May 2010]

synonyms
  • T-cell leukemia homeobox protein 2
  • homeo box 11-like 1
  • homeobox protein Hox-11L1
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Properties