| Protein Name | xanthine dehydrogenase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 7498 |
| Gene Symbol | XDH |
| UniProt | P47989 (XDH_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
285
Total Number of Articles : 460 |
Description |
xanthine dehydrogenase |
| Gene Summary |
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014] |
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