Protein Name glucuronidase, beta
Organism Mus musculus
Gene ID 110006
Gene Symbol

Gusb

UniProt P12265 (BGLR_MOUSE)
Relationships Total Number of functionally related compound(s) : 298
Total Number of Articles : 244
Description

glucuronidase, beta

Gene Summary

Enables beta-glucuronidase activity. Involved in chondroitin sulfate proteoglycan catabolic process; heparan sulfate proteoglycan catabolic process; and hyaluronan catabolic process. Acts upstream of or within carbohydrate metabolic process. Located in extracellular space. Is active in lysosomal lumen. Is expressed in several structures, including alimentary system; brain; heart; sensory organ; and viscerocranium. Used to study mucopolysaccharidosis type VII. Human ortholog(s) of this gene implicated in mucopolysaccharidosis type VII. Orthologous to human GUSB (glucuronidase beta). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • beta-glucuronidase
  • adipose storage deficiency
  • Gur
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Properties