| Protein Name | thioredoxin domain containing 12 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 51060 |
| Gene Symbol | TXNDC12 |
| UniProt | O95881 (TXD12_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
72
Total Number of Articles : 40 |
Description |
thioredoxin domain containing 12 |
| Gene Summary |
This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012] |
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