Protein Name uracil DNA glycosylase
Organism Mus musculus
Gene ID 22256
Gene Symbol

Ung

UniProt P97931 (UNG_MOUSE), Q791V7 (Q791V7_MOUSE)
Relationships Total Number of functionally related compound(s) : 24
Total Number of Articles : 32
Description

uracil DNA glycosylase

Gene Summary

Enables uracil DNA N-glycosylase activity. Acts upstream of or within isotype switching and somatic hypermutation of immunoglobulin genes. Located in mitochondrion and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; lung; and olfactory epithelium. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Orthologous to human UNG (uracil DNA glycosylase). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • uracil-DNA glycosylase
  • UDG
  • UNG1
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Properties