Protein Name ATP synthase F1 subunit epsilon
Organism Homo sapiens
Gene ID 514
Gene Symbol

ATP5F1E

UniProt P56381 (ATP5E_HUMAN)
Relationships Total Number of functionally related compound(s) : 181
Total Number of Articles : 199
Description

ATP synthase F1 subunit epsilon

Gene Summary

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the epsilon subunit of the catalytic core. Two pseudogenes of this gene are located on chromosomes 4 and 13. Read-through transcripts that include exons from this gene are expressed from the upstream gene SLMO2.[provided by RefSeq, Mar 2011]

synonyms
  • ATP synthase F(1) complex subunit epsilon, mitochondrial
  • ATP synthase subunit epsilon, mitochondrial
  • ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
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Properties