CPRiL

Protein Name	sodium voltage-gated channel alpha subunit 10
Organism	Rattus norvegicus
Gene ID	29571
Gene Symbol	Scn10a
UniProt	Q62968 (SCNAA_RAT)
Relationships	Total Number of functionally related compound(s) : 104 Total Number of Articles : 122
Description	sodium voltage-gated channel alpha subunit 10
Gene Summary	Enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential and voltage-gated sodium channel activity. Involved in odontogenesis of dentin-containing tooth and sodium ion transport. Located in axon. Part of clathrin complex. Is active in glutamatergic synapse and presynaptic membrane. Used to study sciatic neuropathy. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 2. Orthologous to human SCN10A (sodium voltage-gated channel alpha subunit 10). [provided by Alliance of Genome Resources, May 2025]
synonyms	sodium channel protein type 10 subunit alpha peripheral nerve sodium channel 3 sensory neuron sodium channel sodium channel protein type X subunit alpha sodium channel type X alpha polypeptide sodium channel voltage-gated type X alpha polypeptide sodium channel, voltage-gated, type 10, alpha polypeptide sodium channel, voltage-gated, type X, alpha subunit voltage-gated sodium channel subunit alpha Nav1.8 Na(V)1.8 Nav1.8 PN3 Click to show/hide the synonyms
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