Protein Name | pre-mRNA processing factor 19 |
---|---|
Organism | Homo sapiens |
Gene ID | 27339 |
Gene Symbol | PRPF19 |
UniProt | Q9UMS4 (PRP19_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
39
Total Number of Articles : 24 |
Description |
pre-mRNA processing factor 19 |
Gene Summary |
Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling; mRNA splicing, via spliceosome; and protein K63-linked ubiquitination. Acts upstream of or within protein polyubiquitination. Located in cytoplasm; nuclear lumen; and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, May 2025] |
synonyms |
|
Properties | |