| Protein Name | tryptophan 2,3-dioxygenase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 56720 |
| Gene Symbol | Tdo2 |
| UniProt | P48776 (T23O_MOUSE), Q8VCW3 (Q8VCW3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
65
Total Number of Articles : 78 |
Description |
tryptophan 2,3-dioxygenase |
| Gene Summary |
Predicted to enable several functions, including heme binding activity; oxygen binding activity; and tryptophan 2,3-dioxygenase activity. Predicted to be involved in L-tryptophan catabolic process to acetyl-CoA; L-tryptophan catabolic process to kynurenine; and protein homotetramerization. Is expressed in cerebellum; liver; male reproductive gland or organ; and small intestine. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Orthologous to human TDO2 (tryptophan 2,3-dioxygenase). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |