Protein Name protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
Organism Rattus norvegicus
Gene ID 25604
Gene Symbol

Pcmt1

UniProt P22062 (PIMT_RAT)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 28
Description

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

Gene Summary

Enables protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. Involved in several processes, including S-adenosylhomocysteine metabolic process; cellular response to hypoxia; and negative regulation of cardiac muscle cell apoptotic process. Located in several cellular components, including basolateral plasma membrane; brush border membrane; and perikaryon. Biomarker of high grade glioma. Orthologous to human PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • protein-L-isoaspartate(D-aspartate) O-methyltransferase
  • L-isoaspartyl protein carboxyl methyltransferase
  • PIMT
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Properties