Protein Name chondroitin sulfate proteoglycan 4
Organism Mus musculus
Gene ID 121021
Gene Symbol

Cspg4

UniProt Q8VHY0 (CSPG4_MOUSE), Q3URZ9 (Q3URZ9_MOUSE)
Relationships Total Number of functionally related compound(s) : 53
Total Number of Articles : 72
Description

chondroitin sulfate proteoglycan 4

Gene Summary

Enables coreceptor activity. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of MAPK cascade; and ruffle assembly. Located in plasma membrane and ruffle. Is expressed in several structures, including alimentary system; brain; genitourinary system; retina; and skeleton. Human ortholog(s) of this gene implicated in relapsing-remitting multiple sclerosis. Orthologous to human CSPG4 (chondroitin sulfate proteoglycan 4). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • chondroitin sulfate proteoglycan 4
  • AN2 proteoglycan
  • AN2/NG2 proteoglycan
Click to show/hide the synonyms
Properties