PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 31085209-0 2019 BPDE and B[a]P induce mitochondrial compromise by ROS-mediated suppression of the SIRT1/TERT/PGC-1alpha pathway in spermatogenic cells both in vitro and in vivo. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 0-4 telomerase reverse transcriptase Sus scrofa 88-92 31085209-0 2019 BPDE and B[a]P induce mitochondrial compromise by ROS-mediated suppression of the SIRT1/TERT/PGC-1alpha pathway in spermatogenic cells both in vitro and in vivo. Benzo(a)pyrene 9-14 telomerase reverse transcriptase Sus scrofa 88-92 31085209-0 2019 BPDE and B[a]P induce mitochondrial compromise by ROS-mediated suppression of the SIRT1/TERT/PGC-1alpha pathway in spermatogenic cells both in vitro and in vivo. Reactive Oxygen Species 50-53 telomerase reverse transcriptase Sus scrofa 88-92 31085209-6 2019 TERT knockdown and re-expression cell models were established to demonstrate that TERT regulated the BPDE-induced mitochondrial damage via PGC-1alpha signaling in GC-2 cells. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 101-105 telomerase reverse transcriptase Sus scrofa 0-4 31085209-6 2019 TERT knockdown and re-expression cell models were established to demonstrate that TERT regulated the BPDE-induced mitochondrial damage via PGC-1alpha signaling in GC-2 cells. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 101-105 telomerase reverse transcriptase Sus scrofa 82-86 31085209-7 2019 Moreover, upregulating or knockdown SIRT1 expression attenuated or aggravated BPDE-induced mitochondrial compromise by activating or inhibiting, respectively, the TERT and PGC-1alpha molecules in GC-2 cells. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 78-82 telomerase reverse transcriptase Sus scrofa 163-167 28552396-12 2017 TSA also enhanced expression of some of pluripotency marker genes (FGF2, LIF, TERT) but their expression was stabilized during further culture without TSA. trichostatin A 0-3 telomerase reverse transcriptase Sus scrofa 78-82