PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 23964850-8 2013 Suppression was significantly reduced in PBMC isolated from T. circumcincta infected vs. helminth-naive lambs, and this reduction in suppression was associated with an increase in Tci-L4-ES antigen-specific T cells within the PBMC. N-Acetyllactosamine 6,6'-Disulfate Disodium Salt 184-186 latexin Mus musculus 180-183 34857289-3 2021 From bio-informatic analyses, as well as data obtained in vitro and in vivo, we find the variations in amino acid sequences lead to only one calcium binding motif in the secondary structure of TCI, compared with three in BCI or PCI. Calcium 141-148 latexin Mus musculus 193-196 34857289-8 2021 Our findings are of great importance for the promotion and wide application of TCI in biomedicine. biomedicine 86-97 latexin Mus musculus 79-82 30643284-2 2019 Here, we introduce alpha-chlorofluoroacetamide (CFA) as a novel warhead of targeted covalent inhibitor (TCI). alpha-chlorofluoroacetamide 19-46 latexin Mus musculus 104-107 30643284-2 2019 Here, we introduce alpha-chlorofluoroacetamide (CFA) as a novel warhead of targeted covalent inhibitor (TCI). 3-chloro-4-fluoroaniline 48-51 latexin Mus musculus 104-107 30643284-9 2019 These results demonstrate the utility of CFA as a new class warheads for TCI. 3-chloro-4-fluoroaniline 41-44 latexin Mus musculus 73-76 28190049-4 2017 Herein we report the preparation of a family of tridentate-chelate-tetrazine derivatives and their Tc(I) complexes. 1,2,3,4-tetrazine 67-76 latexin Mus musculus 99-104 25634699-1 2015 The synthesis, stability, and photophysical properties of [2 + 1] Re(I)/Tc(I) complexes derived from bipyridine and a series of imidazole derivatives were investigated as a means of identifying complexes suitable for creating targeted isostructural optical/nuclear molecular imaging probes. 2,2'-Dipyridyl 101-111 latexin Mus musculus 72-77 25634699-1 2015 The synthesis, stability, and photophysical properties of [2 + 1] Re(I)/Tc(I) complexes derived from bipyridine and a series of imidazole derivatives were investigated as a means of identifying complexes suitable for creating targeted isostructural optical/nuclear molecular imaging probes. imidazole 128-137 latexin Mus musculus 72-77 25341047-6 2014 Ectopic expression of Lxn inhibited FDC-P1 growth in vitro. fdc-p1 36-42 latexin Mus musculus 22-25 25341047-7 2014 More surprisingly, Lxn enhanced gamma irradiation-induced DNA damages and induced cell-cycle arrest and massive necrosis, leading to depletion of FDC-P1 cells. fdc-p1 146-152 latexin Mus musculus 19-22 25341047-10 2014 Moreover, Lxn enhanced the cytotoxicity of chemotherapeutic agent, VP-16, on FDC-P1 cells. Etoposide 67-72 latexin Mus musculus 10-13 25341047-10 2014 Moreover, Lxn enhanced the cytotoxicity of chemotherapeutic agent, VP-16, on FDC-P1 cells. fdc-p1 77-83 latexin Mus musculus 10-13 29664161-3 2018 NMR spectroscopy showed that 1 resisted an off-target thiolate, thus indicating that 1 was a target covalent inhibitor (TCI). thiolate 54-62 latexin Mus musculus 120-123 23964850-8 2013 Suppression was significantly reduced in PBMC isolated from T. circumcincta infected vs. helminth-naive lambs, and this reduction in suppression was associated with an increase in Tci-L4-ES antigen-specific T cells within the PBMC. Einsteinium 187-189 latexin Mus musculus 180-183 22114725-1 2011 BACKGROUND: The imidazoquinoline derivate imiquimod induces inflammatory responses and protection against transplanted tumors when applied to the skin in combination with a cognate peptide epitope (transcutaneous immunization, TCI). THOS Streptonigrin 16-32 latexin Mus musculus 227-230 16823553-0 2006 Synthesis and biological evaluation of tricarbonyl Re(I) and Tc(I) complexes anchored by poly(azolyl)borates: application on the design of radiopharmaceuticals for the targeting of 5-HT1A receptors. poly(azolyl)borates 89-108 latexin Mus musculus 61-66 17220891-3 2007 Using oligonucleotide arrays, real-time PCR and protein blots, we identified latexin (Lxn), a gene whose differential transcription and expression was associated with the allelic differences. Oligonucleotides 6-21 latexin Mus musculus 77-84 17220891-3 2007 Using oligonucleotide arrays, real-time PCR and protein blots, we identified latexin (Lxn), a gene whose differential transcription and expression was associated with the allelic differences. Oligonucleotides 6-21 latexin Mus musculus 86-89