PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
33897280-8	2021	H&E staining of the kidney tissues of the MRL/lpr mice revealed that lncRNA MIAT, as a competitive inhibitor of miR-222, enhanced SLE by upregulating CFHR5 expression through the degradation of miR-222 in vivo.	Helium	0-3	myocardial infarction associated transcript (non-protein coding)	Mus musculus	76-80
33459112-0	2021	LncRNA MIAT downregulates IL-1beta, TNF-alpha to suppress macrophage inflammation but is suppressed by ATP-induced NLRP3 inflammasome activation.	Adenosine Triphosphate	103-106	myocardial infarction associated transcript (non-protein coding)	Mus musculus	7-11
33459112-7	2021	LncRNA MIAT seemed to inhibit the expression of IL-1beta, TNF-alpha and be suppressed by ATP-induced NLRP3 inflammasome activation pathway.	Adenosine Triphosphate	89-92	myocardial infarction associated transcript (non-protein coding)	Mus musculus	7-11
29459686-9	2018	Knockdown of hepatic Gomafu inhibited hepatic glucose production (HGP) and improved insulin sensitivity in obese mice, whereas, overexpression of hepatic Gomafu resulted in an increase in random and fasting blood glucose levels in lean mice.	Glucose	46-53	myocardial infarction associated transcript (non-protein coding)	Mus musculus	21-27
32650294-0	2020	Berberine ameliorates obesity-induced chronic inflammation through suppression of ER stress and promotion of macrophage M2 polarization at least partly via downregulating lncRNA Gomafu.	Berberine	0-9	myocardial infarction associated transcript (non-protein coding)	Mus musculus	178-184
32650294-9	2020	Overexpression of lncRNA Gomafu partially blocked the protective effects of berberine in free fatty acids-treated adipocytes by increasing endoplasmic reticulum stress.	Berberine	76-85	myocardial infarction associated transcript (non-protein coding)	Mus musculus	25-31
32650294-9	2020	Overexpression of lncRNA Gomafu partially blocked the protective effects of berberine in free fatty acids-treated adipocytes by increasing endoplasmic reticulum stress.	Fatty Acids, Nonesterified	89-105	myocardial infarction associated transcript (non-protein coding)	Mus musculus	25-31
32650294-10	2020	Moreover, Gomafu overexpression partly reversed berberine-induced enhancement of M2 polarization in macrophages.	Berberine	48-57	myocardial infarction associated transcript (non-protein coding)	Mus musculus	10-16
32650294-11	2020	Finally, Gomafu overexpression induced ER stress and inflammation in mice, which were improved by berberine administration.	Berberine	98-107	myocardial infarction associated transcript (non-protein coding)	Mus musculus	9-15
30556210-5	2019	Real-time polymerase chain reaction, Western blot analysis, computational analysis, and luciferase assay were conducted to establish a myocardial infarction associated transcript (MIAT) signaling pathway, whose role in the pathogenesis of AHL was further validated by 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay and flow cytometry.	thiazolyl blue	268-329	myocardial infarction associated transcript (non-protein coding)	Mus musculus	180-184
30556210-5	2019	Real-time polymerase chain reaction, Western blot analysis, computational analysis, and luciferase assay were conducted to establish a myocardial infarction associated transcript (MIAT) signaling pathway, whose role in the pathogenesis of AHL was further validated by 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay and flow cytometry.	monooxyethylene trimethylolpropane tristearate	331-334	myocardial infarction associated transcript (non-protein coding)	Mus musculus	180-184
33318298-10	2020	Functionally, AMO-147a or NKAP remitted the beneficial effects of si-MIAT on LPS-induced inflammation response of TC-1 cells.	amo-147a	14-22	myocardial infarction associated transcript (non-protein coding)	Mus musculus	69-73
32556678-2	2020	We aimed to investigate the roles of lncRNA MIAT and miR-330-5p in modulating inflammatory responses and oxidative stress in lipopolysachariden (LPS)-induced septic cardiomyopathy.	lps	145-148	myocardial infarction associated transcript (non-protein coding)	Mus musculus	44-48
32556678-8	2020	Knockdown of MIAT or overexpression of miR-330-5p restrained inflammation and oxidative stress induced by LPS in vitro; MIAT directly targeted miR-330-5p to regulate NF-kappaB signaling, and miR-330-5p targeted against TRAF6 to suppress the activation of NF-kappaB signaling.	lps	106-109	myocardial infarction associated transcript (non-protein coding)	Mus musculus	13-17
32556678-8	2020	Knockdown of MIAT or overexpression of miR-330-5p restrained inflammation and oxidative stress induced by LPS in vitro; MIAT directly targeted miR-330-5p to regulate NF-kappaB signaling, and miR-330-5p targeted against TRAF6 to suppress the activation of NF-kappaB signaling.	lps	106-109	myocardial infarction associated transcript (non-protein coding)	Mus musculus	120-124
32556678-9	2020	We determined that lncRNA MIAT directly binds to miR-330-5p to activate TRAF6/NF-kappaB signaling axis and further promotes inflammation response as well as oxidative stress in LPS-induced septic cardiomyopathy.	lps	177-180	myocardial infarction associated transcript (non-protein coding)	Mus musculus	26-30
32556678-10	2020	This finding suggests the potential therapeutic role of lncRNA MIAT and miR-330-5p in LPS-induced myocardial injury.	lps	86-89	myocardial infarction associated transcript (non-protein coding)	Mus musculus	63-67
32549789-0	2020	MIAT inhibits proliferation of cervical cancer cells through regulating miR-150-5p.	mir-150-5p	72-82	myocardial infarction associated transcript (non-protein coding)	Mus musculus	0-4
30556210-9	2019	Also, MIAT binds to miR-29b, an inhibitor of SIRT1 expression.	mir-29b	20-27	myocardial infarction associated transcript (non-protein coding)	Mus musculus	6-10
30556210-10	2019	The regulatory relationship among MIAT, miR-29b, and SIRT1 was further validated by comparing the differentiated expression of these factors in cells treated with phosphate-buffered saline + H2 O2, a negative control + H2 O2, MIAT + H2 O2 , or H2 O2  + anti-miR-29b.	Phosphate-Buffered Saline	163-188	myocardial infarction associated transcript (non-protein coding)	Mus musculus	34-38
29459686-11	2018	Finally, silenced Foxo1 expression abolished the effect of Gomafu overexpression on gluconeogenesis and glucose production in hepatocytes.	Glucose	104-111	myocardial infarction associated transcript (non-protein coding)	Mus musculus	59-65
27251103-0	2016	Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine.	Methamphetamine	107-122	myocardial infarction associated transcript (non-protein coding)	Mus musculus	0-6
28246353-7	2017	The expressions of MIAT and p-p65 were increased in STZ-induced DM mice and high glucose stimulated rat retinal Muller cells (rMC-1) cells.	Streptozocin	52-55	myocardial infarction associated transcript (non-protein coding)	Mus musculus	19-23
28246353-7	2017	The expressions of MIAT and p-p65 were increased in STZ-induced DM mice and high glucose stimulated rat retinal Muller cells (rMC-1) cells.	Glucose	81-88	myocardial infarction associated transcript (non-protein coding)	Mus musculus	19-23
34953943-8	2022	Overall, these results indicate that MIAT participates in CS-induced EMT and airway remodeling in COPD by upregulating miR-29c-3p-HIF3A axis output, thereby offering a novel promising biomarker for the assessment of COPD exacerbation induced by CS exposure.	Cesium	58-60	myocardial infarction associated transcript (non-protein coding)	Mus musculus	37-41
33819189-7	2021	The results of in vitro and in vivo experimentation also suggested that overexpression of miR-10a-5p or silencing of MIAT and EGR2 reduced cardiomyocyte apoptosis and increased ATP content, thus alleviating the impairment of cardiac function following MI.	Adenosine Triphosphate	177-180	myocardial infarction associated transcript (non-protein coding)	Mus musculus	117-121
34953943-8	2022	Overall, these results indicate that MIAT participates in CS-induced EMT and airway remodeling in COPD by upregulating miR-29c-3p-HIF3A axis output, thereby offering a novel promising biomarker for the assessment of COPD exacerbation induced by CS exposure.	Cesium	245-247	myocardial infarction associated transcript (non-protein coding)	Mus musculus	37-41
34650678-3	2021	6-hydroxydopamine-induced SH-SY5Y cell lines and a PD mouse model were used to prove how the overexpressing or knocking-down of MIAT produce a marked effect in both in vitro and in vivo experiments.	Oxidopamine	0-17	myocardial infarction associated transcript (non-protein coding)	Mus musculus	128-132
34709954-4	2021	AR mice were treated with miR-10b-5p agomiR and LNA mediated lncRNA MIAT.	mir-10b-5p	26-36	myocardial infarction associated transcript (non-protein coding)	Mus musculus	68-72
34709954-14	2021	CONCLUSION: The present study demonstrates that MIAT overexpression Promotes allergic inflammation and symptoms by activating Th17 immune response via miR-10b-5p inhibition.	mir-10b-5p	151-161	myocardial infarction associated transcript (non-protein coding)	Mus musculus	48-52
35000421-6	2022	We also develop DTG (double TG) mice overexpressing MIAT and miR-150.	1-(4-azido-2-methylphenyl)-3-(2-methylphenyl)guanidine	16-19	myocardial infarction associated transcript (non-protein coding)	Mus musculus	52-56
34989253-0	2022	Curcumin improves atherosclerosis by inhibiting the epigenetic repression of lncRNA MIAT to miR-124.	Curcumin	0-8	myocardial infarction associated transcript (non-protein coding)	Mus musculus	84-88
34981118-0	2022	Lidocaine relieves spinal cord ischemia-reperfusion injury via long non-coding RNA MIAT-mediated Notch1 downregulation.	Lidocaine	0-9	myocardial infarction associated transcript (non-protein coding)	Mus musculus	83-87
34981118-2	2022	This study aimed to investigate whether lidocaine relieves SCIRI via modulating MIAT-mediated Notch1 downregulation.	Lidocaine	40-49	myocardial infarction associated transcript (non-protein coding)	Mus musculus	80-84
34981118-8	2022	After lidocaine treatment, MIAT expression was elevated in lipopolysaccharide- (LPS-) induced BV2 cells.	Lidocaine	6-15	myocardial infarction associated transcript (non-protein coding)	Mus musculus	27-31
35347106-10	2022	Besides, serum-EVs could transfer MIAT (EV-MIAT) into osteosarcoma cells, where it is competitively bound to miR-613 to elevate GPR158, thus promoting osteosarcoma cell proliferation and angiogenesis.	mir-613	109-116	myocardial infarction associated transcript (non-protein coding)	Mus musculus	34-38
35347106-10	2022	Besides, serum-EVs could transfer MIAT (EV-MIAT) into osteosarcoma cells, where it is competitively bound to miR-613 to elevate GPR158, thus promoting osteosarcoma cell proliferation and angiogenesis.	mir-613	109-116	myocardial infarction associated transcript (non-protein coding)	Mus musculus	43-47
35079871-0	2022	Knockdown of lncRNA MIAT attenuated lipopolysaccharide-induced microglial cells injury by sponging miR-613.	mir-613	99-106	myocardial infarction associated transcript (non-protein coding)	Mus musculus	20-24
34989253-11	2022	MIAT overexpression and miR-124 inhibition relieved the anti-inflammation effect of curcumin in ox-LDL-induced cell.	Curcumin	84-92	myocardial infarction associated transcript (non-protein coding)	Mus musculus	0-4
34989253-13	2022	Curcumin relieved ox-LDL-induced cell inflammation via regulating MIAT/miR-124 pathway.	Curcumin	0-8	myocardial infarction associated transcript (non-protein coding)	Mus musculus	66-70
34989253-14	2022	Conclusion: MIAT/miR-124 axis mediated the effect of curcumin on atherosclerosis and altered cell apoptosis and proliferation, both in vivo and in vitro.	Curcumin	53-61	myocardial infarction associated transcript (non-protein coding)	Mus musculus	12-16
34967706-6	2022	Dual-luciferase reporter gene assays were performed to determine the interaction of miR-221-3p with MIAT or TGFB receptor 1 (TGFBR1).	mir-221-3p	84-94	myocardial infarction associated transcript (non-protein coding)	Mus musculus	100-104
34967706-11	2022	LncRNA MIAT promoted MPP+-induced neuronal injury in PD via regulating TGF-beta1/Nrf2 axis through binding with miR-221-3p.	mangion-purified polysaccharide (Candida albicans)	21-25	myocardial infarction associated transcript (non-protein coding)	Mus musculus	7-11