PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
28276496-5	2017	Thus, MTCH2 is a critical player in neuronal cell biology, controlling mitochondria metabolism, motility and calcium buffering to regulate hippocampal-dependent cognitive functions.	Calcium	109-116	mitochondrial carrier 2	Mus musculus	6-11
30401654-1	2018	Mitochondrial Carrier Homolog 2 (MTCH2) acts as a receptor for the BH3 interacting-domain death agonist (BID) in the mitochondrial outer membrane.	BH 3	67-70	mitochondrial carrier 2	Mus musculus	0-31
30401654-1	2018	Mitochondrial Carrier Homolog 2 (MTCH2) acts as a receptor for the BH3 interacting-domain death agonist (BID) in the mitochondrial outer membrane.	BH 3	67-70	mitochondrial carrier 2	Mus musculus	33-38
22326460-1	2012	Recent studies report mitochondrial carrier homolog 2 (MTCH2) as a novel and uncharacterized protein that acts as a receptor-like protein for the truncated BH3-interacting domain death agonist (tBID) protein in the outer membrane of mitochondria.	tBID	194-198	mitochondrial carrier 2	Mus musculus	22-53
27320914-4	2016	Subsequent tBid recruitment to mitochondria, which is facilitated by its receptor MTCH2 at the outer mitochondrial membrane (OMM), is a critical step for commitment to apoptosis via the effector proteins Bax or Bak.	tBID	11-15	mitochondrial carrier 2	Mus musculus	82-87
27320914-8	2016	MOAP-1 binds to MTCH2, and this interaction appears necessary for MTCH2 to engage tBid.	tBID	82-86	mitochondrial carrier 2	Mus musculus	66-71
27320914-9	2016	These findings reveal a role for MOAP-1 in Fas signaling in the liver by promoting MTCH2-mediated tBid recruitment to mitochondria.	tBID	98-102	mitochondrial carrier 2	Mus musculus	83-88
26876167-4	2016	Moreover, metabolic profiling of mice deficient in muscle MTCH2 reveals a preference for carbohydrate utilization and an increase in mitochondria and glycolytic flux in muscles.	Carbohydrates	89-101	mitochondrial carrier 2	Mus musculus	58-63
27359329-0	2016	Mimp/Mtch2, an Obesity Susceptibility Gene, Induces Alteration of Fatty Acid Metabolism in Transgenic Mice.	Fatty Acids	66-76	mitochondrial carrier 2	Mus musculus	5-10
27359329-8	2016	Moreover, high-fat diet-fed Mimp/Mtch2 mice exhibit high blood glucose levels.	Glucose	63-70	mitochondrial carrier 2	Mus musculus	33-38
22326460-1	2012	Recent studies report mitochondrial carrier homolog 2 (MTCH2) as a novel and uncharacterized protein that acts as a receptor-like protein for the truncated BH3-interacting domain death agonist (tBID) protein in the outer membrane of mitochondria.	tBID	194-198	mitochondrial carrier 2	Mus musculus	55-60
22326460-2	2012	These studies, using mouse embryonic stem cells and fibroblasts as well as mice with a conditional knockout of MTCH2 in the liver, showed that deletion of MTCH2 hindered recruitment of tBID to the mitochondria with subsequent reductions in the activation of pro-apoptotic proteins, mitochondrial outer membrane permeabilization and apoptosis.	tBID	185-189	mitochondrial carrier 2	Mus musculus	155-160
22326460-5	2012	There are extensive differences between the protein sequences of MTCH2 and other mitochondrial carriers that may explain the ability of MTCH2 to associate with tBID and thus its role in apoptosis.	tBID	160-164	mitochondrial carrier 2	Mus musculus	65-70
22326460-5	2012	There are extensive differences between the protein sequences of MTCH2 and other mitochondrial carriers that may explain the ability of MTCH2 to associate with tBID and thus its role in apoptosis.	tBID	160-164	mitochondrial carrier 2	Mus musculus	136-141
20436477-0	2010	MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.	methyl inosine monophosphate	6-10	mitochondrial carrier 2	Mus musculus	0-5
20436477-0	2010	MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.	tBID	37-41	mitochondrial carrier 2	Mus musculus	0-5
20436477-2	2010	Here we show that MTCH2/MIMP (mitochondrial carrier homologue 2/Met-induced mitochondrial protein), a novel truncated BID (tBID)-interacting protein, is a surface-exposed outer mitochondrial membrane protein that facilitates the recruitment of tBID to mitochondria.	methyl inosine monophosphate	24-28	mitochondrial carrier 2	Mus musculus	18-23
20436477-2	2010	Here we show that MTCH2/MIMP (mitochondrial carrier homologue 2/Met-induced mitochondrial protein), a novel truncated BID (tBID)-interacting protein, is a surface-exposed outer mitochondrial membrane protein that facilitates the recruitment of tBID to mitochondria.	tBID	123-127	mitochondrial carrier 2	Mus musculus	18-23
20436477-2	2010	Here we show that MTCH2/MIMP (mitochondrial carrier homologue 2/Met-induced mitochondrial protein), a novel truncated BID (tBID)-interacting protein, is a surface-exposed outer mitochondrial membrane protein that facilitates the recruitment of tBID to mitochondria.	tBID	244-248	mitochondrial carrier 2	Mus musculus	18-23
20436477-3	2010	Knockout of MTCH2/MIMP in embryonic stem cells and in mouse embryonic fibroblasts hinders the recruitment of tBID to mitochondria, the activation of Bax/Bak, MOMP, and apoptosis.	tBID	109-113	mitochondrial carrier 2	Mus musculus	12-17
20436477-4	2010	Moreover, conditional knockout of MTCH2/MIMP in the liver decreases the sensitivity of mice to Fas-induced hepatocellular apoptosis and prevents the recruitment of tBID to liver mitochondria both in vivo and in vitro.	methyl inosine monophosphate	40-44	mitochondrial carrier 2	Mus musculus	34-39
20436477-4	2010	Moreover, conditional knockout of MTCH2/MIMP in the liver decreases the sensitivity of mice to Fas-induced hepatocellular apoptosis and prevents the recruitment of tBID to liver mitochondria both in vivo and in vitro.	ammonium ferrous sulfate	95-98	mitochondrial carrier 2	Mus musculus	34-39
20436477-4	2010	Moreover, conditional knockout of MTCH2/MIMP in the liver decreases the sensitivity of mice to Fas-induced hepatocellular apoptosis and prevents the recruitment of tBID to liver mitochondria both in vivo and in vitro.	tBID	164-168	mitochondrial carrier 2	Mus musculus	34-39
20436477-6	2010	These loss-of-function models indicate that MTCH2/MIMP has a critical function in liver apoptosis by regulating the recruitment of tBID to mitochondria.	tBID	131-135	mitochondrial carrier 2	Mus musculus	44-49
15899861-0	2005	Mitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha.	tBID	47-51	mitochondrial carrier 2	Mus musculus	0-31
15899861-10	2005	These results implicate Mtch2 as a mitochondrial target of tBID and raise the possibility that the Mtch2-resident complex participates in the mitochondrial apoptotic program.	tBID	59-63	mitochondrial carrier 2	Mus musculus	24-29
33652185-0	2021	Silica nanoparticles inducing the apoptosis via microRNA-450b-3p targeting MTCH2 in mice and spermatocyte cell.	Silicon Dioxide	0-6	mitochondrial carrier 2	Mus musculus	75-80
33652185-8	2021	In vitro, the mimic of miRNA-450 b-3p reversed the decrease of viability and the increase of apoptosis rate and significantly antagonized the expression enhancements of the MTCH2, BID, BAX, Cytochrome C, Caspase-9, Caspase-3 induced by SiNPs, while inhibitor of miRNA-450 b-3p further promoted the effects induced by SiNPs.	mirna-450 b-3p	23-37	mitochondrial carrier 2	Mus musculus	173-178