PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
11245789-0	2001	The rapid mode of calcium uptake into heart mitochondria (RaM): comparison to RaM in liver mitochondria.	Calcium	18-25	CCDC26 long non-coding RNA	Homo sapiens	58-61
11245789-11	2001	RaM in liver mitochondria is strongly activated by spermine, activated by ATP or GTP and unaffected by ADP and AMP.	Spermine	51-59	CCDC26 long non-coding RNA	Homo sapiens	0-3
11245789-11	2001	RaM in liver mitochondria is strongly activated by spermine, activated by ATP or GTP and unaffected by ADP and AMP.	Adenosine Triphosphate	74-77	CCDC26 long non-coding RNA	Homo sapiens	0-3
11245789-11	2001	RaM in liver mitochondria is strongly activated by spermine, activated by ATP or GTP and unaffected by ADP and AMP.	Guanosine Triphosphate	81-84	CCDC26 long non-coding RNA	Homo sapiens	0-3
3089329-1	1986	Here we show that ram mutations, either in ribosomal protein S4 or S5, decrease the proofreading flows for both cognate and noncognate ternary complexes bound by streptomycin-dependent (SmD) ribosomes.	Streptomycin	162-174	CCDC26 long non-coding RNA	Homo sapiens	18-21
11245789-12	2001	In heart, RaM is activated much less strongly by spermine and unaffected by ATP or GTP.	Spermine	49-57	CCDC26 long non-coding RNA	Homo sapiens	10-13
11245789-13	2001	RaM in heart is strongly inhibited by AMP and has a biphasic response to ADP; it is activated at low concentrations and inhibited at high concentrations.	Adenosine Monophosphate	38-41	CCDC26 long non-coding RNA	Homo sapiens	0-3
11245789-13	2001	RaM in heart is strongly inhibited by AMP and has a biphasic response to ADP; it is activated at low concentrations and inhibited at high concentrations.	Adenosine Diphosphate	73-76	CCDC26 long non-coding RNA	Homo sapiens	0-3
10692860-6	1999	The defect in steroid hormone production by the adult testes of the male-oriented ram may represent a defect that can be traced to the fetal testes.	Steroids	14-29	CCDC26 long non-coding RNA	Homo sapiens	82-85
9772054-9	1998	The two patients failing RAM treatment had metronidazole-resistant strains before and after treatment.	Metronidazole	43-56	CCDC26 long non-coding RNA	Homo sapiens	25-28
34249914-0	2021	Desmosterol Incorporation Into Ram Sperm Membrane Before Cryopreservation Improves in vitro and in vivo Fertility.	Desmosterol	0-11	CCDC26 long non-coding RNA	Homo sapiens	31-34
34249914-2	2021	Sensitivity of ram sperm to freeze-thawing is related to the lipid composition of the membrane, particularly to its low sterol content.	Sterols	120-126	CCDC26 long non-coding RNA	Homo sapiens	15-18
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	Sterols	25-31	CCDC26 long non-coding RNA	Homo sapiens	43-46
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	Sterols	25-31	CCDC26 long non-coding RNA	Homo sapiens	240-243
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	methyl-beta-cyclodextrin	88-112	CCDC26 long non-coding RNA	Homo sapiens	43-46
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	methyl-beta-cyclodextrin	88-112	CCDC26 long non-coding RNA	Homo sapiens	240-243
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	Sterols	113-119	CCDC26 long non-coding RNA	Homo sapiens	43-46
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	Cholesterol	205-216	CCDC26 long non-coding RNA	Homo sapiens	43-46
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	Cholesterol	205-216	CCDC26 long non-coding RNA	Homo sapiens	240-243
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	Desmosterol	221-232	CCDC26 long non-coding RNA	Homo sapiens	43-46
34249914-3	2021	Recently, we proved that sterol content of ram sperm can be increased by treatment with methyl-beta-cyclodextrin-sterol complexes and we provided mechanistic based evidence on the differential behavior of cholesterol and desmosterol in the ram sperm membrane.	Desmosterol	221-232	CCDC26 long non-coding RNA	Homo sapiens	240-243
34249914-4	2021	In the present study, we evaluated the role of increasing cholesterol and desmosterol content of ram sperm before cryopreservation, on the extent and distribution of sterols, cryocapacitation status, acrosome integrity, DNA damage associated with apoptosis and fertility competence in vitro and in vivo of post-thawed sperm.	Desmosterol	74-85	CCDC26 long non-coding RNA	Homo sapiens	97-100
34249914-9	2021	Tyrosine phosphorylation was significantly lower when ram sperm incorporated cholesterol compared to the control.	Tyrosine	0-8	CCDC26 long non-coding RNA	Homo sapiens	54-57
34249914-9	2021	Tyrosine phosphorylation was significantly lower when ram sperm incorporated cholesterol compared to the control.	Cholesterol	77-88	CCDC26 long non-coding RNA	Homo sapiens	54-57
34249914-15	2021	Our research provides new insights on sterol incorporation into ram sperm prior to cryopreservation, in particular on the additional benefit of incorporating desmosterol as a strategy to improve fertility outcome.	Sterols	38-44	CCDC26 long non-coding RNA	Homo sapiens	64-67
34113488-9	2021	Knockdown of CCDC26 and LINC01515 increased the sensitivity of K562/ADR cells to doxorubicin and significantly reduced the half-maximal inhibitory concentration (IC50) of doxorubicin.	Doxorubicin	81-92	CCDC26 long non-coding RNA	Homo sapiens	13-19
34113488-9	2021	Knockdown of CCDC26 and LINC01515 increased the sensitivity of K562/ADR cells to doxorubicin and significantly reduced the half-maximal inhibitory concentration (IC50) of doxorubicin.	Doxorubicin	171-182	CCDC26 long non-coding RNA	Homo sapiens	13-19
33340546-5	2021	We showed that expression of embryonic (epsilon- and zeta-) globins was markedly upregulated in CCDC26-KD cells compared with K562 control cells during hemin-induced differentiation.	Hemin	152-157	CCDC26 long non-coding RNA	Homo sapiens	96-102
32213234-4	2020	Chemical composition analysis of RAM showed that the main compositions were volatile oil, lactones, polysaccharides, amino acids, vitamins and resins.	Oils	85-88	CCDC26 long non-coding RNA	Homo sapiens	33-36
32213234-4	2020	Chemical composition analysis of RAM showed that the main compositions were volatile oil, lactones, polysaccharides, amino acids, vitamins and resins.	Polysaccharides	100-115	CCDC26 long non-coding RNA	Homo sapiens	33-36
31296830-1	2019	The present study reports the outcomes of chemotherapy using nab-PTXplus RAM in 6 patients with metastatic gastric cancer as recommended in the JGCA guidelines for special conditions.	nab	61-64	CCDC26 long non-coding RNA	Homo sapiens	73-76
28229947-5	2017	A proof of concept production of hydrated and anhydrous cocrystals of 1:1 Theophylline Citric acid system at a 400mg scale was demonstrated using solvent and bead assisted RAM.	Theophylline	74-86	CCDC26 long non-coding RNA	Homo sapiens	172-175
30316685-2	2018	Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen species (ROS) in the regulation of SAM and RAM functions in response to nitrogen availability.	Nitrogen	54-62	CCDC26 long non-coding RNA	Homo sapiens	156-159
30316685-2	2018	Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen species (ROS) in the regulation of SAM and RAM functions in response to nitrogen availability.	Nitric Oxide	74-86	CCDC26 long non-coding RNA	Homo sapiens	156-159
30316685-2	2018	Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen species (ROS) in the regulation of SAM and RAM functions in response to nitrogen availability.	Reactive Oxygen Species	97-120	CCDC26 long non-coding RNA	Homo sapiens	156-159
30316685-2	2018	Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen species (ROS) in the regulation of SAM and RAM functions in response to nitrogen availability.	Reactive Oxygen Species	122-125	CCDC26 long non-coding RNA	Homo sapiens	156-159
30316685-2	2018	Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen species (ROS) in the regulation of SAM and RAM functions in response to nitrogen availability.	Nitrogen	185-193	CCDC26 long non-coding RNA	Homo sapiens	156-159
29702366-0	2018	Effects of melatonin administration on seminal plasma metabolites and sperm fertilization competence during the non-reproductive season in ram.	Melatonin	11-20	CCDC26 long non-coding RNA	Homo sapiens	139-142
29702366-1	2018	The purpose of this study was to investigate the effects of ram melatonin treatment on the sperm quality and metabolite composition of the seminal plasma in the non-breeding season.	Melatonin	64-73	CCDC26 long non-coding RNA	Homo sapiens	60-63
29702366-6	2018	Ram melatonin treatment affected the in vitro fertilization competence of sperm.	Melatonin	4-13	CCDC26 long non-coding RNA	Homo sapiens	0-3
29702366-8	2018	In treated rams, the concentration of melatonin in seminal plasma increased from 3.34 +- 1.70 at day 0-9.65 +- 2.89 AU (Arbitrary Units) after 90 days, then decreased to reach the level of the untreated ram after 120 days (p < 0.05).	Melatonin	38-47	CCDC26 long non-coding RNA	Homo sapiens	11-14
29702366-11	2018	In conclusion, melatonin treatment during the non-breeding season improves the concentration of several metabolites in seminal plasma and sperm fertilization competence in Sarda breed ram.	Melatonin	15-24	CCDC26 long non-coding RNA	Homo sapiens	184-187
31166382-0	2019	Downregulation of lncRNA CCDC26 contributes to imatinib resistance in human gastrointestinal stromal tumors through IGF-1R upregulation.	Imatinib Mesylate	47-55	CCDC26 long non-coding RNA	Homo sapiens	25-31
31166382-6	2019	The expression of a series of reported drug resistance-related lncRNAs, including CCDC26, ARF, H19, NBR2, NEAT1, and HOTAIR, in GIST cells treated with imatinib H19 was examined at various time-points by qRT-PCR.	Imatinib Mesylate	152-160	CCDC26 long non-coding RNA	Homo sapiens	82-88
31166382-7	2019	Based on our results and published literature, CCDC26, a strongly down-regulated lncRNA following imatinib treatment, was chosen as our research target.	Imatinib Mesylate	98-106	CCDC26 long non-coding RNA	Homo sapiens	47-53
31166382-8	2019	GIST cells with high expression of CCDC26 were sensitive to imatinib treatment while knockdown of CCDC26 significantly increased the resistance to imatinib.	Imatinib Mesylate	60-68	CCDC26 long non-coding RNA	Homo sapiens	35-41
31166382-8	2019	GIST cells with high expression of CCDC26 were sensitive to imatinib treatment while knockdown of CCDC26 significantly increased the resistance to imatinib.	Imatinib Mesylate	147-155	CCDC26 long non-coding RNA	Homo sapiens	98-104
31166382-10	2019	Moreover, IGF-1R inhibition reversed CCDC26 knockdown-mediated imatinib resistance in GIST.	Imatinib Mesylate	63-71	CCDC26 long non-coding RNA	Homo sapiens	37-43
31166382-11	2019	These results indicated that treatments targeting CCDC26-IGF-1R axis would be useful in increasing sensitivity to imatinib in GIST.	Imatinib Mesylate	114-122	CCDC26 long non-coding RNA	Homo sapiens	50-56
29423012-0	2018	CCDC26 knockdown enhances resistance of gastrointestinal stromal tumor cells to imatinib by interacting with c-KIT.	Imatinib Mesylate	80-88	CCDC26 long non-coding RNA	Homo sapiens	0-6
29423012-3	2018	In the present study, we explored the biological function of the lncRNA coiled-coil domain-containing 26 (CCDC26) in imatinib resistance of GIST.	Imatinib Mesylate	117-125	CCDC26 long non-coding RNA	Homo sapiens	106-112
29423012-4	2018	We found that human GIST-882 cells with lower CCDC26 expression were less sensitive to imatinib compared with GIST-T1 cells with higher CCDC26 expression.	Imatinib Mesylate	87-95	CCDC26 long non-coding RNA	Homo sapiens	46-52
29423012-5	2018	CCDC26 expression decreased in a time-dependent manner in the presence of imatinib.	Imatinib Mesylate	74-82	CCDC26 long non-coding RNA	Homo sapiens	0-6
29423012-6	2018	Moreover, small interfering RNA (siRNA) knockdown of CCDC26 increased GIST cell sensitivity to imatinib.	Imatinib Mesylate	95-103	CCDC26 long non-coding RNA	Homo sapiens	53-59
29423012-9	2018	Lastly, we proved that inhibiting c-KIT can reverse CCDC26 knockdown-mediated imatinib resistance in GIST.	Imatinib Mesylate	78-86	CCDC26 long non-coding RNA	Homo sapiens	52-58
29423012-10	2018	We suggest that CCDC26 knockdown can induce imatinib resistance in GIST cells by downregulating c-KIT expression.	Imatinib Mesylate	44-52	CCDC26 long non-coding RNA	Homo sapiens	16-22
28229947-5	2017	A proof of concept production of hydrated and anhydrous cocrystals of 1:1 Theophylline Citric acid system at a 400mg scale was demonstrated using solvent and bead assisted RAM.	Citric Acid	87-98	CCDC26 long non-coding RNA	Homo sapiens	172-175
28229947-8	2017	A quantitative XRPD method was developed to determine the extent of conversion to the cocrystal when using RAM Mixing time of 2h and an acceleration of 60G were determined to be optimal.	Deuterium	126-128	CCDC26 long non-coding RNA	Homo sapiens	107-110
27890594-0	2017	An investigation of trends in precious metal and copper content of RAM modules in WEEE: Implications for long term recycling potential.	Copper	49-55	CCDC26 long non-coding RNA	Homo sapiens	67-70