PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9816169-0	1996	Suramin increases p53 protein levels but does not activate the p53-dependent G1 checkpoint.	Suramin	0-7	transformation related protein 53, pseudogene	Mus musculus	18-21	
9816169-2	1996	We have investigated whether the induction of growth arrest by suramin requires the p53 protein, a tumor suppressor gene product involved in the initiation of growth arrest following DNA damage.	Suramin	63-70	transformation related protein 53, pseudogene	Mus musculus	84-87	
9816169-5	1996	Exposure of NIH-3T3 cells to suramin caused a rapid (1-2 h) increase in the level of p53-DNA-binding activity.	Suramin	29-36	transformation related protein 53, pseudogene	Mus musculus	85-88	
9816169-8	1996	If NIH-3T3 cells were exposed to radiation or suramin plus radiation, p21 mRNA levels were increased and cyclin-dependent kinase 2 kinase activity was inhibited, indicating that suramin does not block the cells" ability to increase p21 levels.	Suramin	46-53	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	70-73	
9816169-8	1996	If NIH-3T3 cells were exposed to radiation or suramin plus radiation, p21 mRNA levels were increased and cyclin-dependent kinase 2 kinase activity was inhibited, indicating that suramin does not block the cells" ability to increase p21 levels.	Suramin	46-53	cyclin-dependent kinase 2	Mus musculus	105-130	
9816169-11	1996	Suramin increases p53 protein levels, but fails to increase p21 mRNA levels or to activate the G1 checkpoint.	Suramin	0-7	transformation related protein 53, pseudogene	Mus musculus	18-21