PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9777037-3 1998 The activity of the enzyme acetylcholinesterase was also evaluated in diverse structures of the central nervous system after the intracerebral administration of neostigmine. Neostigmine 161-172 acetylcholinesterase Rattus norvegicus 27-47 9777037-10 1998 Because the used route of administration of neostigmine, a greater degree of inhibition of the hypothalamic acetylcholinesterase is observed, suggesting then that the hypothalamic structures could be involved in the cardiovascular effects induced by the intracerebral administration of the anticholinesterase. Neostigmine 44-55 acetylcholinesterase Rattus norvegicus 108-128