PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9774447-0	1998	Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK).	Paclitaxel	0-10	mitogen-activated protein kinase 8	Homo sapiens	124-132	
9774447-0	1998	Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK).	Paclitaxel	12-17	mitogen-activated protein kinase 8	Homo sapiens	124-132	
9774447-7	1998	Paclitaxel activated JNK, and to a lesser degree p38, but not ERK1.	Paclitaxel	0-10	mitogen-activated protein kinase 8	Homo sapiens	21-24	
9774447-8	1998	Paclitaxel-induced IL-8 promoter activation was inhibited by dominant-inhibitory mutants of JNK, p38, and the super-repressor form of IkappaBalpha, but not by dominant-inhibitory forms of ERK1.	Paclitaxel	0-10	mitogen-activated protein kinase 8	Homo sapiens	92-95	
9774447-9	1998	Dominant-inhibitory mutants of JNK1 also greatly reduced paclitaxel-induced cell death, and the kinetics of JNK induction was closely followed by DNA fragmentation.	Paclitaxel	57-67	mitogen-activated protein kinase 8	Homo sapiens	31-35	
9774447-9	1998	Dominant-inhibitory mutants of JNK1 also greatly reduced paclitaxel-induced cell death, and the kinetics of JNK induction was closely followed by DNA fragmentation.	Paclitaxel	57-67	mitogen-activated protein kinase 8	Homo sapiens	31-34	
9774447-10	1998	These results indicate (i) that paclitaxel activates the JNK signaling pathway and (ii) that JNK activation is a common point of paclitaxel-induced gene induction and cell death.	Paclitaxel	32-42	mitogen-activated protein kinase 8	Homo sapiens	57-60	
9774447-10	1998	These results indicate (i) that paclitaxel activates the JNK signaling pathway and (ii) that JNK activation is a common point of paclitaxel-induced gene induction and cell death.	Paclitaxel	129-139	mitogen-activated protein kinase 8	Homo sapiens	93-96