PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9656574-0	1998	[Theophylline reduces serum levels of ECP in vitro].	Theophylline	1-13	ribonuclease A family member 3	Homo sapiens	38-41	
9656574-1	1998	Measurement of serum levels of ECP has been widely used for monitoring airway inflammation in bronchial asthma and recently been applied to measure anti-inflammatory effect of theophylline.	Theophylline	176-188	ribonuclease A family member 3	Homo sapiens	31-34	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	34-46	ribonuclease A family member 3	Homo sapiens	27-30	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	34-46	ribonuclease A family member 3	Homo sapiens	175-178	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	34-46	ribonuclease A family member 3	Homo sapiens	175-178	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	108-120	ribonuclease A family member 3	Homo sapiens	27-30	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	108-120	ribonuclease A family member 3	Homo sapiens	27-30	
9656574-3	1998	In order to answer the question, we tested whether theophylline added to blood after sampling reduces measured levels of serum ECP.	Theophylline	51-63	ribonuclease A family member 3	Homo sapiens	127-130	
9656574-6	1998	Theophylline significantly reduced serum ECP in a concentration-dependent manner.	Theophylline	0-12	ribonuclease A family member 3	Homo sapiens	41-44	
9656574-7	1998	Percent reduction of ECP levels at 1 hour of incubation were 11.9%, 18.7%, 22.8%, and 51.7% at theophylline levels of 5, 12.5, 22.5, and 120 micrograms/ml, respectively.	Theophylline	95-107	ribonuclease A family member 3	Homo sapiens	21-24	
9656574-8	1998	Kinetics of serum ECP release was also inhibited in the presence of theophylline.	Theophylline	68-80	ribonuclease A family member 3	Homo sapiens	18-21	
9656574-9	1998	These results suggest that in vitro effect of theophylline on serum ECP levels should be considered when data of serum ECP in patients who take theophylline are interpreted.	Theophylline	46-58	ribonuclease A family member 3	Homo sapiens	68-71	
9656574-9	1998	These results suggest that in vitro effect of theophylline on serum ECP levels should be considered when data of serum ECP in patients who take theophylline are interpreted.	Theophylline	46-58	ribonuclease A family member 3	Homo sapiens	119-122	
9656574-9	1998	These results suggest that in vitro effect of theophylline on serum ECP levels should be considered when data of serum ECP in patients who take theophylline are interpreted.	Theophylline	144-156	ribonuclease A family member 3	Homo sapiens	68-71	
9656574-9	1998	These results suggest that in vitro effect of theophylline on serum ECP levels should be considered when data of serum ECP in patients who take theophylline are interpreted.	Theophylline	144-156	ribonuclease A family member 3	Homo sapiens	119-122