PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9642110-3 1998 We have previously shown that moderate stimulation of CD4(+)CD8(+) thymocytes with a combination of the calcium ionophore ionomycin and phorbol myristate acetate mimics positive selection events including downregulation of CD8 expression. Ionomycin 122-131 CD8a molecule Homo sapiens 60-63 9642110-3 1998 We have previously shown that moderate stimulation of CD4(+)CD8(+) thymocytes with a combination of the calcium ionophore ionomycin and phorbol myristate acetate mimics positive selection events including downregulation of CD8 expression. Ionomycin 122-131 CD8a molecule Homo sapiens 223-226