PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9609323-1 1998 Levels of the DNA promutagenic methylation damage, O6-methylguanine (O6-MeG) and the activity of the O6-methylguanine-DNA methyltransferase (MGMT), the enzyme responsible for repairing O6-MeG, were measured at various time intervals in tissues of BDF-I mice administered a single therapeutic dose of the antischistosomal agents hycanthone, oxaminiquine and metrifonate. O-(6)-methylguanine 51-67 O-6-methylguanine-DNA methyltransferase Mus musculus 141-145 9609323-1 1998 Levels of the DNA promutagenic methylation damage, O6-methylguanine (O6-MeG) and the activity of the O6-methylguanine-DNA methyltransferase (MGMT), the enzyme responsible for repairing O6-MeG, were measured at various time intervals in tissues of BDF-I mice administered a single therapeutic dose of the antischistosomal agents hycanthone, oxaminiquine and metrifonate. O-(6)-methylguanine 69-75 O-6-methylguanine-DNA methyltransferase Mus musculus 141-145 9609323-1 1998 Levels of the DNA promutagenic methylation damage, O6-methylguanine (O6-MeG) and the activity of the O6-methylguanine-DNA methyltransferase (MGMT), the enzyme responsible for repairing O6-MeG, were measured at various time intervals in tissues of BDF-I mice administered a single therapeutic dose of the antischistosomal agents hycanthone, oxaminiquine and metrifonate. O-(6)-methylguanine 185-191 O-6-methylguanine-DNA methyltransferase Mus musculus 101-139 9609323-1 1998 Levels of the DNA promutagenic methylation damage, O6-methylguanine (O6-MeG) and the activity of the O6-methylguanine-DNA methyltransferase (MGMT), the enzyme responsible for repairing O6-MeG, were measured at various time intervals in tissues of BDF-I mice administered a single therapeutic dose of the antischistosomal agents hycanthone, oxaminiquine and metrifonate. O-(6)-methylguanine 185-191 O-6-methylguanine-DNA methyltransferase Mus musculus 141-145 9609323-5 1998 Hepatic MGMT in these animals was significantly lower (approximately 38%) than the control values after 6 h, then restored by 48 h. A significant negative correlation was obtained between O6-MeG and MGMT activity in the liver (r=- 0.85), intestine (r=- 0.62) and bladder (r=- 0.59). O-(6)-methylguanine 188-194 O-6-methylguanine-DNA methyltransferase Mus musculus 8-12 9609323-5 1998 Hepatic MGMT in these animals was significantly lower (approximately 38%) than the control values after 6 h, then restored by 48 h. A significant negative correlation was obtained between O6-MeG and MGMT activity in the liver (r=- 0.85), intestine (r=- 0.62) and bladder (r=- 0.59). O-(6)-methylguanine 188-194 O-6-methylguanine-DNA methyltransferase Mus musculus 199-203