PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9507016-0	1998	All-trans-retinoic acid inhibits Jun N-terminal kinase-dependent signaling pathways.	Tretinoin	0-23	mitogen-activated protein kinase 8	Homo sapiens	33-54	
9507016-4	1998	In this study, we examined MAP kinase-dependent pathways as potential targets of retinoid signaling and the role of MAP kinases in retinoid-induced c-fos gene regulation.	Retinoids	131-139	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	148-153	
9507016-5	1998	All-trans-retinoic acid (t-RA) inhibited Jun N-terminal kinase (JNK) and, to a lesser extent, extracellular signal-regulated kinase activity in normal HBE cells.	Tretinoin	0-23	mitogen-activated protein kinase 8	Homo sapiens	41-62	
9507016-5	1998	All-trans-retinoic acid (t-RA) inhibited Jun N-terminal kinase (JNK) and, to a lesser extent, extracellular signal-regulated kinase activity in normal HBE cells.	Tretinoin	0-23	mitogen-activated protein kinase 8	Homo sapiens	64-67	
9507016-5	1998	All-trans-retinoic acid (t-RA) inhibited Jun N-terminal kinase (JNK) and, to a lesser extent, extracellular signal-regulated kinase activity in normal HBE cells.	Tretinoin	25-29	mitogen-activated protein kinase 8	Homo sapiens	41-62	
9507016-5	1998	All-trans-retinoic acid (t-RA) inhibited Jun N-terminal kinase (JNK) and, to a lesser extent, extracellular signal-regulated kinase activity in normal HBE cells.	Tretinoin	25-29	mitogen-activated protein kinase 8	Homo sapiens	64-67	
9507016-8	1998	Furthermore, c-fos expression was inhibited by agonists of retinoic acid receptors (RARs) or retinoid X receptors (RXRs), and suppression of c-fos promoter activity by t-RA was abrogated by treatment with antagonists of RAR-alpha or of all the RXRs.	Tretinoin	168-172	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	13-18	
9507016-8	1998	Furthermore, c-fos expression was inhibited by agonists of retinoic acid receptors (RARs) or retinoid X receptors (RXRs), and suppression of c-fos promoter activity by t-RA was abrogated by treatment with antagonists of RAR-alpha or of all the RXRs.	Tretinoin	168-172	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	141-146	
9507016-8	1998	Furthermore, c-fos expression was inhibited by agonists of retinoic acid receptors (RARs) or retinoid X receptors (RXRs), and suppression of c-fos promoter activity by t-RA was abrogated by treatment with antagonists of RAR-alpha or of all the RXRs.	Tretinoin	168-172	retinoic acid receptor alpha	Homo sapiens	220-229	
9507016-11	1998	In light of the growth activation induced by JNK/SEK-dependent pathways in a variety of cells, these data support further investigation into the role of JNK-dependent signaling in the growth-suppressive effects of retinoids.	Retinoids	214-223	mitogen-activated protein kinase 8	Homo sapiens	45-48	
9507016-11	1998	In light of the growth activation induced by JNK/SEK-dependent pathways in a variety of cells, these data support further investigation into the role of JNK-dependent signaling in the growth-suppressive effects of retinoids.	Retinoids	214-223	EPH receptor A4	Homo sapiens	49-52	
9507016-11	1998	In light of the growth activation induced by JNK/SEK-dependent pathways in a variety of cells, these data support further investigation into the role of JNK-dependent signaling in the growth-suppressive effects of retinoids.	Retinoids	214-223	mitogen-activated protein kinase 8	Homo sapiens	153-156