PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9502784-8 1998 Finally, the C609W HSCR mutation exerts a dual effect on RET since it leads to a decrease of the receptor at the cell surface and converted RET51 into a constitutively activated kinase due to the formation of disulfide-linked homodimers. Disulfides 209-218 ret proto-oncogene Homo sapiens 57-60 9502784-8 1998 Finally, the C609W HSCR mutation exerts a dual effect on RET since it leads to a decrease of the receptor at the cell surface and converted RET51 into a constitutively activated kinase due to the formation of disulfide-linked homodimers. Disulfides 209-218 ret proto-oncogene Homo sapiens 140-145