PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9493318-5 1998 Among the hepatic microsomal P450-dependent monooxygenase activities tested, testosterone 2 alpha-hydroxylase (T2AH) activity in the male rat, which is associated with CYP2C11, was decreased by both cis- and trans-1,2-DCE isomers. TRANS-1,2-DICHLOROETHYLENE 208-221 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 168-175 9493318-8 1998 The levels of testosterone 6 beta-hydroxylase (T6BH) activity and CYP3A2/1 protein in the male rat were reduced by cis-1,2-DCE but not trans-1,2-DCE. CIS-1,2-DICHLOROETHYLENE 115-126 cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus 14-45 9493318-8 1998 The levels of testosterone 6 beta-hydroxylase (T6BH) activity and CYP3A2/1 protein in the male rat were reduced by cis-1,2-DCE but not trans-1,2-DCE. CIS-1,2-DICHLOROETHYLENE 115-126 cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus 47-51 9493318-8 1998 The levels of testosterone 6 beta-hydroxylase (T6BH) activity and CYP3A2/1 protein in the male rat were reduced by cis-1,2-DCE but not trans-1,2-DCE. CIS-1,2-DICHLOROETHYLENE 115-126 cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus 66-74 9493318-10 1998 cis-1,2-DCE decreased ethoxycoumarin O-deethylase (ECOD), benzyloxyresorufin O-debenzylase (BROD), chlorzoxazone 6-hydroxylase (CZ6H) and testosterone 7 alpha-hydroxylase (T7AH) activities in the male rat by 29, 28, 34 and 27% respectively. CIS-1,2-DICHLOROETHYLENE 0-11 cytochrome P450, family 2, subfamily a, polypeptide 1 Rattus norvegicus 138-170