PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9481610-6 1997 L-CHANNEL CALCIUM ANTAGONISTS: Depending on their pharmacodynamic characteristics, L-channel calcium antagonists of the dihydropyridine, verapamil or diltiazem type reflexly activate the sympathetic nervous system and blunt beta-adrenoceptor-mediated calcium influx, thus eliciting negative inotropy and activation of the renin-angiotensin system. Diltiazem 150-159 renin Homo sapiens 322-327