PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9461566-8 1998 Assaying ERK5 activity in immune complexes with one of these substrates, c-Myc, we determined that the ERK5 catalytic domain is activated by V12 H-Ras and to a lesser extent by phorbol ester but not by constitutively active mutants of Raf-1. Phorbol Esters 177-190 MYC proto-oncogene, bHLH transcription factor Homo sapiens 73-78