PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9357097-4 1997 This interaction was probably mediated by an inhibiting action of ketoconazole on cytochrome CYP3A4, the main enzyme responsible for CBZ metabolism. Carbamazepine 133-136 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 93-99