PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9276732-6 1997 This alteration in eicosanoid metabolism was associated with induction of cyclooxygenase (Cox)-2 and thromboxane synthase, but not Cox-1. Eicosanoids 19-29 mitochondrially encoded cytochrome c oxidase II Homo sapiens 74-96 9276732-7 1997 Unlike results seen in other systems, the upregulation of Cox-2 and the subsequent release of eicosanoids by endothelial cells was not directly induced by complement but rather required production of IL-1alpha, which acted on endothelial cells as an autocrine factor. Eicosanoids 94-105 mitochondrially encoded cytochrome c oxidase II Homo sapiens 58-63