PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9172017-0 1996 Differential regulation of TNF alpha, IL-1 beta, IL-6, IL-8, TNF beta, and IL-10 by pentoxifylline. Pentoxifylline 84-98 interleukin 6 Homo sapiens 49-53 9172017-3 1996 We investigated PTX effects on production and mRNA expression of TNF alpha, IL-1 beta, IL-6, IL-8, TNF beta and IL-10. Pentoxifylline 16-19 interleukin 6 Homo sapiens 87-91 9172017-7 1996 Moreover, we observed that depending on the way of activating cells, PTX induced an up- or a down-regulation (in PMA + PHA or LPS stimulated cells, respectively) for IL-1 and IL-6 release. Pentoxifylline 69-72 interleukin 6 Homo sapiens 175-179 9172017-8 1996 We also noted that the effects of PTX on IL-6, IL-8 and IL-10 production were different in WB and in PBMC culture. Pentoxifylline 34-37 interleukin 6 Homo sapiens 41-45