PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9067893-6	1997	ET-1-induced activation of JNK was blocked by BQ-123, an antagonist for the ETA receptor.	cyclo(Trp-Asp-Pro-Val-Leu)	46-52	endothelin 1	Homo sapiens	0-4	
9067893-6	1997	ET-1-induced activation of JNK was blocked by BQ-123, an antagonist for the ETA receptor.	cyclo(Trp-Asp-Pro-Val-Leu)	46-52	mitogen-activated protein kinase 8	Homo sapiens	27-30	
9067893-7	1997	The depletion of PKC by prolonged treatment with phorbol 12,13 dibutyrate or the inhibition of PKC by GF 109203X failed to inhibit ET-1-induced activation of JNK.	bisindolylmaleimide I	102-112	proline rich transmembrane protein 2	Homo sapiens	95-98	
9067893-8	1997	In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA).	Calcium	73-80	endothelin 1	Homo sapiens	13-17	
9067893-8	1997	In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA).	Calcium	73-80	mitogen-activated protein kinase 8	Homo sapiens	40-43	
9067893-8	1997	In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA).	1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid	97-102	endothelin 1	Homo sapiens	13-17	
9067893-8	1997	In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA).	1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid	97-102	mitogen-activated protein kinase 8	Homo sapiens	40-43	
9067893-8	1997	In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA).	Egtazic Acid	110-114	endothelin 1	Homo sapiens	13-17	
9067893-8	1997	In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA).	Egtazic Acid	110-114	mitogen-activated protein kinase 8	Homo sapiens	40-43	
9067893-9	1997	In addition, ionomycin, a calcium ionophore, and thapsigargin, an intracellular calcium-rising agent, were able to induce the activation of JNK.	Ionomycin	13-22	mitogen-activated protein kinase 8	Homo sapiens	140-143	
9067893-9	1997	In addition, ionomycin, a calcium ionophore, and thapsigargin, an intracellular calcium-rising agent, were able to induce the activation of JNK.	Calcium	26-33	mitogen-activated protein kinase 8	Homo sapiens	140-143	
9067893-9	1997	In addition, ionomycin, a calcium ionophore, and thapsigargin, an intracellular calcium-rising agent, were able to induce the activation of JNK.	Thapsigargin	49-61	mitogen-activated protein kinase 8	Homo sapiens	140-143	
9067893-9	1997	In addition, ionomycin, a calcium ionophore, and thapsigargin, an intracellular calcium-rising agent, were able to induce the activation of JNK.	Calcium	80-87	mitogen-activated protein kinase 8	Homo sapiens	140-143	
9067893-10	1997	ET-1-induced activation of JNK was also inhibited by PTK inhibitors (herbimycin A and genistein).	herbimycin	69-81	endothelin 1	Homo sapiens	0-4	
9067893-10	1997	ET-1-induced activation of JNK was also inhibited by PTK inhibitors (herbimycin A and genistein).	herbimycin	69-81	mitogen-activated protein kinase 8	Homo sapiens	27-30	
9067893-10	1997	ET-1-induced activation of JNK was also inhibited by PTK inhibitors (herbimycin A and genistein).	herbimycin	69-81	protein tyrosine kinase 2 beta	Homo sapiens	53-56	
9067893-10	1997	ET-1-induced activation of JNK was also inhibited by PTK inhibitors (herbimycin A and genistein).	Genistein	86-95	endothelin 1	Homo sapiens	0-4	
9067893-10	1997	ET-1-induced activation of JNK was also inhibited by PTK inhibitors (herbimycin A and genistein).	Genistein	86-95	mitogen-activated protein kinase 8	Homo sapiens	27-30	
9067893-10	1997	ET-1-induced activation of JNK was also inhibited by PTK inhibitors (herbimycin A and genistein).	Genistein	86-95	protein tyrosine kinase 2 beta	Homo sapiens	53-56	
9067893-12	1997	These results indicate that ET-1 is able to activate JNK in glomerular mesangial cells through PKC-independent and PTK-dependent pathways and intracellular calcium is necessary to the activation of JNK.	Calcium	156-163	mitogen-activated protein kinase 8	Homo sapiens	198-201