PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8894516-5	1996	Ciprofloxacin and norfloxacin significantly depressed the N-demethylation of erythromycin by CYP3A4 in human microsomes and by CYP3A2 in rat microsomes.	Ciprofloxacin	0-13	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	93-99	
8894516-5	1996	Ciprofloxacin and norfloxacin significantly depressed the N-demethylation of erythromycin by CYP3A4 in human microsomes and by CYP3A2 in rat microsomes.	Ciprofloxacin	0-13	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	127-133	
8894516-5	1996	Ciprofloxacin and norfloxacin significantly depressed the N-demethylation of erythromycin by CYP3A4 in human microsomes and by CYP3A2 in rat microsomes.	Norfloxacin	18-29	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	93-99	
8894516-5	1996	Ciprofloxacin and norfloxacin significantly depressed the N-demethylation of erythromycin by CYP3A4 in human microsomes and by CYP3A2 in rat microsomes.	Norfloxacin	18-29	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	127-133	
8894516-5	1996	Ciprofloxacin and norfloxacin significantly depressed the N-demethylation of erythromycin by CYP3A4 in human microsomes and by CYP3A2 in rat microsomes.	Nitrogen	58-59	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	93-99	
8894516-5	1996	Ciprofloxacin and norfloxacin significantly depressed the N-demethylation of erythromycin by CYP3A4 in human microsomes and by CYP3A2 in rat microsomes.	Erythromycin	77-89	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	93-99	
8894516-10	1996	These studies in hepatic microsomes demonstrate that fluoroquinolones can decrease CYP3A- and CYP1A-mediated biotransformation by competitive inhibition and that they have the potential to cause drug interactions with agents metabolized by these enzymes.	Fluoroquinolones	53-69	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	83-88