PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8663428-3 1996 Transient expression of activated Galpha12 increased the percentage of Ras in the active, GTP-bound state, stimulated c-Jun NH2-terminal kinase (JNK) activity, and enhanced the transcriptional activity of c-Jun. Guanosine Triphosphate 90-93 G protein subunit alpha 12 Homo sapiens 34-42 8663428-7 1996 These data demonstrate that the alpha subunit of the heterotrimeric G protein G12, like tyrosine kinase growth factor receptors, activates Ras and recruits a signal transduction pathway involving the small GTP-binding protein Rac that leads to JNK activation. Guanosine Triphosphate 206-209 AKT serine/threonine kinase 1 Homo sapiens 226-229 8663428-7 1996 These data demonstrate that the alpha subunit of the heterotrimeric G protein G12, like tyrosine kinase growth factor receptors, activates Ras and recruits a signal transduction pathway involving the small GTP-binding protein Rac that leads to JNK activation. Guanosine Triphosphate 206-209 mitogen-activated protein kinase 8 Homo sapiens 244-247