PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8654369-7 1996 The HSCR972 (Arg972-->Gly) mutation, mapping in the intracytoplasmic region of RET, impaired its tyrosine kinase activity, while two extracellular mutations, HSCR32 (Ser32-->Leu) and HSCR393 (Phe393-->Leu), inhibited the biological activity of RET by impairing the correct maturation of the RET protein and its transport to the cell surface. Glycine 25-28 ret proto-oncogene Homo sapiens 82-85