PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8647935-0	1996	Immunosuppressant FK506 induces interleukin-6 production through the activation of transcription factor nuclear factor (NF)-kappa(B).	Tacrolimus	18-23	interleukin 6	Homo sapiens	32-45	
8647935-4	1996	We further show that FK506 induces NF-kappaB-regulated IL-6 production in vitro and in vivo, in particular in kidney.	Tacrolimus	21-26	interleukin 6	Homo sapiens	55-59	
8647935-7	1996	These results thus suggest a causal relationship between FK506-induced NF-kappaB activation/IL-6 production and some of FK506-induced renal abnormalities.	Tacrolimus	57-62	interleukin 6	Homo sapiens	92-96	
8647935-7	1996	These results thus suggest a causal relationship between FK506-induced NF-kappaB activation/IL-6 production and some of FK506-induced renal abnormalities.	Tacrolimus	120-125	interleukin 6	Homo sapiens	92-96