PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8618029-4	1996	Based on histamine release from IgE-sensitized and nonsensitized basophil leukocytes of healthy donors, we detected anti-Fc epsilon RI alpha autoantibodies in sera from 38 (23%) urticaria patients and evidence for anti-IgE antibodies in a further nine patients.	Histamine	9-18	Fc epsilon receptor Ia	Homo sapiens	121-140	
8618029-7	1996	Preincubation of sera or the IgG fraction with a recombinant alpha-chain of Fc epsilon RI inhibited histamine release from mast cells and basophils.	Histamine	100-109	Fc gamma receptor and transporter	Homo sapiens	61-72	
8618029-7	1996	Preincubation of sera or the IgG fraction with a recombinant alpha-chain of Fc epsilon RI inhibited histamine release from mast cells and basophils.	Histamine	100-109	Fc epsilon receptor Ia	Homo sapiens	76-89	
8618029-9	1996	These studies demonstrate that circulating levels of anti-Fc epsilon RI alpha autoantibodies mediate histamine release from skin mast cells in vitro and, taken together with in vivo evidence of mast cell degranulation following intradermal injection of autologous serum, support the concept that anti-Fc epsilon RI alpha autoantibodies are relevant to the pathogenesis of severe chronic urticaria in about 25% of patients.	Histamine	101-110	Fc epsilon receptor Ia	Homo sapiens	58-77