PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8423554-0	1993	Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A).	Mephenytoin	53-64	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	85-90	
8423554-0	1993	Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A).	Mephenytoin	53-64	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	95-100	
8423554-5	1993	Antibodies raised against CYP2C11 (anti-CYP2C) clearly inhibited microsomal 4"-hydroxylation of S-mephenytoin and N-demethylation of R-mephenytoin in rats, monkeys and humans.	Mephenytoin	96-109	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	26-33	
8423554-5	1993	Antibodies raised against CYP2C11 (anti-CYP2C) clearly inhibited microsomal 4"-hydroxylation of S-mephenytoin and N-demethylation of R-mephenytoin in rats, monkeys and humans.	Mephenytoin	96-109	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	26-31	
8423554-5	1993	Antibodies raised against CYP2C11 (anti-CYP2C) clearly inhibited microsomal 4"-hydroxylation of S-mephenytoin and N-demethylation of R-mephenytoin in rats, monkeys and humans.	(R)-(-)-Mephenytoin	133-146	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	26-33	
8423554-5	1993	Antibodies raised against CYP2C11 (anti-CYP2C) clearly inhibited microsomal 4"-hydroxylation of S-mephenytoin and N-demethylation of R-mephenytoin in rats, monkeys and humans.	(R)-(-)-Mephenytoin	133-146	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	26-31	
8423554-6	1993	Antibodies raised against CYP3A2 (anti-CYP3A) clearly inhibited microsomal 4"-hydroxylation of R-mephenytoin, but marginally S-mephenytoin, in rats.	(R)-(-)-Mephenytoin	95-108	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	26-32	
8423554-6	1993	Antibodies raised against CYP3A2 (anti-CYP3A) clearly inhibited microsomal 4"-hydroxylation of R-mephenytoin, but marginally S-mephenytoin, in rats.	(R)-(-)-Mephenytoin	95-108	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	26-31	
8423554-6	1993	Antibodies raised against CYP3A2 (anti-CYP3A) clearly inhibited microsomal 4"-hydroxylation of R-mephenytoin, but marginally S-mephenytoin, in rats.	Mephenytoin	125-138	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	26-32	
8423554-6	1993	Antibodies raised against CYP3A2 (anti-CYP3A) clearly inhibited microsomal 4"-hydroxylation of R-mephenytoin, but marginally S-mephenytoin, in rats.	Mephenytoin	125-138	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	26-31	
8423554-8	1993	The results suggest that stereoselective involvement of rat CYP3A and scant involvement of human CYP3A in R-mephenytoin 4"-hydroxylation are major determinants of the species differences between rats and humans in stereoselective mephenytoin 4"-hydroxylation.	(R)-(-)-Mephenytoin	106-119	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	97-102