PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8226746-13 1993 These results suggest that the alpha-meso-hydroxylation required for biliverdin formation is mediated by the distal of the two oxygens in the iron-dioxygen intermediate (Fe-O-O) engendered by reaction with either cytochrome P450 reductase/NADPH or H2O2. NADP 239-244 cytochrome p450 oxidoreductase Rattus norvegicus 213-238