PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8064238-0	1994	Allele specificity of structural requirement for peptides bound to HLA-DRB1*0405 and -DRB1*0406 complexes: implication for the HLA-associated susceptibility to methimazole-induced insulin autoimmune syndrome.	Methimazole	160-171	major histocompatibility complex, class II, DR beta 1	Homo sapiens	67-75	
8064238-0	1994	Allele specificity of structural requirement for peptides bound to HLA-DRB1*0405 and -DRB1*0406 complexes: implication for the HLA-associated susceptibility to methimazole-induced insulin autoimmune syndrome.	Methimazole	160-171	major histocompatibility complex, class II, DR beta 1	Homo sapiens	71-75	
8064238-0	1994	Allele specificity of structural requirement for peptides bound to HLA-DRB1*0405 and -DRB1*0406 complexes: implication for the HLA-associated susceptibility to methimazole-induced insulin autoimmune syndrome.	Methimazole	160-171	major histocompatibility complex, class II, DR beta 1	Homo sapiens	67-70	
8064238-5	1994	It is noteworthy that all patients with methimazole-induced insulin autoimmune syndrome are positive for DRB1*0406 and negative for DRB1*0405.	Methimazole	40-51	major histocompatibility complex, class II, DR beta 1	Homo sapiens	105-109	
8064238-5	1994	It is noteworthy that all patients with methimazole-induced insulin autoimmune syndrome are positive for DRB1*0406 and negative for DRB1*0405.	Methimazole	40-51	major histocompatibility complex, class II, DR beta 1	Homo sapiens	132-136	
8064238-9	1994	Although this fragment probably exists at a very low level under normal physiological conditions due to the disulfide bond between flanking cysteine residues (6Cys-11Cys), a reducing compound such as methimazole may cleave the disulfide bond in vivo and allow DR alpha-DRB1*0406 complex on antigen-presenting cells to bind much of the linear fragment of insulin alpha chain, which may lead to the activation of self-insulin-specific T-helper cells.	Methimazole	200-211	major histocompatibility complex, class II, DR beta 1	Homo sapiens	269-273