PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7893669-9 1995 Comparison of Kd values with corresponding Km values suggested both strong cooperativity (6,8-dimethylpterin) and antagonism (6-methyl-8-isopropylpterin) with NADPH in binding to DHFR. NADP 159-164 dihydrofolate reductase Gallus gallus 179-183