PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7882901-5 1994 When tested by RIA or by the Nb2 bioassay, there appeared to be approximately 50% less PRL secreted (2 weeks post-injection) by cells of the NMU-treated than the vehicle-treated animals. Methylnitrosourea 141-144 prolactin Rattus norvegicus 87-90 7882901-6 1994 However, when tested by IL-2R assay, PRL cells of NMU-treated animals secreted 50% more activity. Methylnitrosourea 50-53 prolactin Rattus norvegicus 37-40 7882901-9 1994 Our interpretation is that NMU treatment interferes with the feedback of lymphokines on the pituitary with a decrease in the form of PRL detected by the RIA and Nb2 assays and an increase in the form which activates splenocytes, and thus changes the composition and function of the immune system. Methylnitrosourea 27-30 prolactin Rattus norvegicus 133-136