PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7761100-0	1995	MDM2 protein confers the resistance of a human glioblastoma cell line to cisplatin-induced apoptosis.	Cisplatin	73-82	MDM2 proto-oncogene	Homo sapiens	0-4	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	125-153	transformation related protein 53, pseudogene	Mus musculus	61-64	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	125-153	transformed mouse 3T3 cell double minute 2	Mus musculus	69-73	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	125-153	transformed mouse 3T3 cell double minute 2	Mus musculus	75-97	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	125-153	tumor protein p53	Homo sapiens	253-256	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	125-153	MDM2 proto-oncogene	Homo sapiens	261-265	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	155-164	transformation related protein 53, pseudogene	Mus musculus	61-64	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	155-164	transformed mouse 3T3 cell double minute 2	Mus musculus	69-73	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	155-164	transformed mouse 3T3 cell double minute 2	Mus musculus	75-97	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	155-164	tumor protein p53	Homo sapiens	253-256	
7761100-4	1995	In this study, we show that the expression of both wild-type p53 and MDM2 (murine double minute 2) proteins was induced when cis-diamminedichloroplatinum (cisplatin) caused apoptosis in human glioblastoma U87-MG cells, which expressed neither wild-type p53 nor MDM2 protein prior to treatment.	Cisplatin	155-164	MDM2 proto-oncogene	Homo sapiens	261-265	
7761100-5	1995	Overexpression of MDM2 in U87-MG cells transfected with human mdm2 expression vector conferred the resistance of tumor cell to cisplatin-induced apoptosis.	Cisplatin	127-136	MDM2 proto-oncogene	Homo sapiens	18-22	
7761100-5	1995	Overexpression of MDM2 in U87-MG cells transfected with human mdm2 expression vector conferred the resistance of tumor cell to cisplatin-induced apoptosis.	Cisplatin	127-136	MDM2 proto-oncogene	Homo sapiens	62-66	
7761100-6	1995	In contrast, the treatment with mdm2 antisense oligonucleotide targeted against mdm2 mRNA increased the susceptibility of tumor cells to apoptosis.	Oligonucleotides	47-62	MDM2 proto-oncogene	Homo sapiens	32-36	
7761100-6	1995	In contrast, the treatment with mdm2 antisense oligonucleotide targeted against mdm2 mRNA increased the susceptibility of tumor cells to apoptosis.	Oligonucleotides	47-62	MDM2 proto-oncogene	Homo sapiens	80-84	
7761100-8	1995	These findings suggest that MDM2 protein may act as a negative regulator of cisplatin-induced apoptosis, and moreover, may play an important role in the development of resistance to cisplatin in human tumors.	Cisplatin	76-85	MDM2 proto-oncogene	Homo sapiens	28-32	
7761100-8	1995	These findings suggest that MDM2 protein may act as a negative regulator of cisplatin-induced apoptosis, and moreover, may play an important role in the development of resistance to cisplatin in human tumors.	Cisplatin	182-191	MDM2 proto-oncogene	Homo sapiens	28-32